Job ID: 289590765  |  Last Updated: 6/25/2018

Application Computational Scientist / Bioinformatics Analyst / Research Data Analyst

Employer
The Jackson Labratory
Location
Bar Harbor, ME
Applicant Contact
Mandi Marcino
Accepts J-1 Visas
Unspecified
Websites

Job Description

The Jackson Laboratory is immediately seeking an Application Computational Scientist/Bioinformatics Analyst I-III/Research Data Analyst I-II to join our Computational Sciences group. These positions offer the opportunity to make leading contributions to cutting edge research in mouse genetics, disease biology, and translational research in collaboration with the faculty and genetic resource scientists and clients of The Jackson Laboratory (JAX). Cross campus and industry collaborations are encouraged.

These positions have primary responsibility for providing statistical and analytical bioinformatics expertise and interpretation in the scientific research programs at the Jackson Laboratory and its collaborative programs.

Key Responsibilities:
Develop, apply, maintain, and support cutting-edge pipelines for the analysis and interpretation of NGS data (DNA-Seq, RNA-Seq, ChIP-Seq, Bisulphite-Seq, ATAC-Seq etc.)
Dockerize and deployment of pipelines on cloud based computing environments (google cloud, AWS, Seven Bridges Systems)
Work with other scientists and developers to benchmark both internally and externally developed tools/pipelines to stay on the cutting edge of NGS data analysis
Help research faculty in experimental design of sequencing experiments and perform analysis of genetic & genomic data (in particular cancer genomic data)
Develop novel methods/tools to address the research questions
Perform genome assembly, finishing, genome annotation, variation detection, comparative genomics using state-of-the-art tools
Stay aware of emerging trends in NGS analysis processes and maintain expertise in application of genomic technologies
Working effectively in a team environment with individuals with varying levels of experience
Contribute to the drafting of manuscripts and grants


Requirements:
MS or PhD degree in Computational Biology, Bioinformatics, Genetics/Computer science (with significant Bioinformatics expertise) or related field. Recent graduates with relevant degree and expertise are encouraged to apply.
Candidates with a proven track record of omics data analysis (in particular in cloud environment), method development, independent collaborative work and leading contributions to a biological discipline would be given preference.
Solid knowledge of scripting languages (Perl, Python, R or Ruby), and Unix OS are strictly required.
Solid understanding of Illumina, and Pacific BioSciences Sequencing technology.
Experience working with Docker containers and cloud-based compute environments.
Experience with large genomic datasets including TCGA, ENCODE, 1000 Genomes Project, ExAC, gnomAD and related resources.
Experience in applying/developing computational algorithms and systems to support genetics and genomics research.
Experience with popular NGS analysis software (BWA, bowtie, GATK-suite, RSEM, SnpEff etc.)
Experience with de novo assembly software programs such Velvet, HGAP, ALLPATHS-LG, SOAPdenovo 2 and MIRA4 etc.
Strong track record of peer-reviewed publication in relevant scientific journals.
Independent decision making capabilities related to projects, excellent communication skills including skills necessary to present at the conferences and workshops, write study designs and analytical methods.


About us:
The Jackson Laboratory (JAX, www.jax.org) is a nonprofit biomedical research institute with over 2,000 employees whose mission is to discover precise genomic solutions for human disease and empower the global biomedical community in the shared quest to improve human health. A National Cancer Institute-designated Cancer Center, JAX has a mammalian genetics headquarters in Bar Harbor, Maine; JAXWest, a facility in Sacramento, Calif.; and The Jackson Laboratory for Genomic Medicine (JAX-GM), a genomic medicine facility in Farmington, Conn., that is enabling the Laboratory to translate its fundamental science into the clinic.

The Jackson Laboratory's 43-acre scenic Bar Harbor campus is nestled between the Gulf of Maine and the mountains of Acadia National Park. Some of the best hiking and biking in the world (over 50 square miles of mountains, lakes, views, and dramatic coastline) is accessible from our campus. We are one mile from downtown Bar Harbor, which offers a vibrant downtown district with a plethora of restaurants, shops, museums, and galleries.

JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 Best Places to Work in Academia in the United States in a poll conducted by The Scientist magazine!



Our Values:
INTEGRITY - Courage and commitment to do what is right

PEOPLE - Inspiring our people to enhance the health of all

ONE TEAM - Unified by our promise to transform medicine and science

EXCELLENCE - Achieving world-class results

INNOVATION - Leading with discovery and creative solutions

STEWARDSHIP - Caring for and enhancing the resources entrusted to us


What do we have to offer?
JAX offers a dynamic and supportive work environment, competitive salaries, and a comprehensive benefits package, including a medical plan, outstanding retirement plan, generous paid time off, and tuition reimbursement. JAX offers an MBA program, a fitness center with an award-winning wellness program, and a fully operational primary care facility available to employees and their families.

Most importantly, every position contributes to JAXs mission of discovering precise genomic solutions for human disease and empowering the global biomedical community in our shared quest to improve human health.

The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.

Learn more about career opportunities at JAX: http://www.jax.org/careers.

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